Response of a co-culture model of epithelial cells and gingival fibroblasts to zoledronic acid

• Main Authors: Fernanda Gonçalves BASSO (Author), Diana Gabriela SOARES (Author), Taisa Nogueira PANSANI (Author), Ana Paula Silveira TURRIONI (Author), Débora Lopes SCHEFFEL (Author), Josimeri HEBLING (Author), Carlos Alberto de Souza COSTA (Author)
• Format: Book
• Published: Sociedade Brasileira de Pesquisa Odontológica.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Osteonecrosis of the jaw is an adverse effect of bisphosphonates. While the etiopathogenesis of this condition has been investigated, the interactions and effects of bisphosphonates on oral mucosa cells remain unclear. It is hypothesized that cell culture models, such as co-culture or three...