F127-SE-tLAP thermosensitive hydrogel alleviates bleomycin-induced skin fibrosis via TGF-β/Smad pathway

• Main Authors: Zhiqin Cao (Author), Keke Zhang (Author), Jingruo Liu (Author), Yu Pan (Author), Jiayi Shi (Author), Luxin Li (Author), Xiaocan Sun (Author), Shiqi Li (Author), Xiaohuan Yuan (Author), Dan Wu (Author)
• Format: Book
• Published: BMC, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skin fibrosis affects the normal function of the skin. TGF-β1 is a key cytokine that affects organ fibrosis. The latency-associated peptide (LAP) is essential for TGF-β1 activation. We previously constructed and prepared truncated LAP (tLAP), and confirmed that tLAP inhibited liv...