Interleukin-1β Affects MDAMB231 Breast Cancer Cell Migration under Hypoxia: Role of HIF-1α and NFκB Transcription Factors

• Autori principali: Irene Filippi (Autore), Fabio Carraro (Autore), Antonella Naldini (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2015-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Inflammation and tumor hypoxia are intimately linked and breast cancer provides a typical example of an inflammation-linked malignant disease. Indeed, breast cancer progression is actively supported by inflammatory components, including IL-1β, and by the hypoxia-inducible factor- (HIF-) 1α. In spite...