DsbA-L activates TGF-β1/SMAD3 signaling and M2 macrophage polarization by stimulating AKT1 and NLRP3 to promote pulmonary fibrosis

• 主要な著者: Juan Wang (著者), Zhenkun Xia (著者), Bei Qing (著者), Ying Chen (著者), Linguo Gu (著者), Hongzuo Chen (著者), Zhenglian Ge (著者), Yunchang Yuan (著者)
• フォーマット: 図書
• 出版事項: BMC, 2024-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Pulmonary fibrosis (PF) is a progressive and difficult-to-heal lung disease that poses a significant threat to human life and health. This study aimed to investigate the potential pathological mechanisms of PF and to identify new avenues for the treatment of PF. Methods Clinical...