Can ivermectin mass treatments eliminate onchocerciasis in Africa?

• Main Authors: Winnen M. (Author), Plaisier A.P (Author), Alley E.S (Author), Nagelkerke N.J.D (Author), van Oortmarssen G. (Author), Boatin B.A (Author), Habbema J.D.F (Author)
• Format: Book
• Published: The World Health Organization, 2002-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

OBJECTIVE: To elucidate the conditions in which mass treatment with ivermectin reduces the transmission of Onchocerca volvulus sufficiently to eliminate infection from an African community. METHODS: ONCHOSIM, a microsimulation model for onchocerciasis transmission, was used to explore the implicatio...