Computed tomography and photoacoustic imaging guided photodynamic therapy against breast cancer based on mesoporous platinum with insitu oxygen generation ability

• Main Authors: Lingyan Zhang (Author), Mifang Li (Author), Quan Zhou (Author), Meng Dang (Author), Yuxia Tang (Author), Shouju Wang (Author), Jijun Fu (Author), Zhaogang Teng (Author), Guangming Lu (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Photodynamic therapy (PDT) has been widely used in cancer treatment. However, hypoxia in most solid tumors seriously restricts the efficacy of PDT. To improve the hypoxic microenvironment, we designed a novel mesoporous platinum (mPt) nanoplatform to catalyze hydrogen peroxide (H2O2) within the tumo...