ASK1-P38 Pathway is Important for Anoikis Induced by Microtubule-Targeting Aryl Chloroethylureas

• Hauptverfasser: Jessica S Fortin (Verfasst von), Alexandre Patenaude (Verfasst von), Rena G Deschesnes (Verfasst von), Marie-France Côté (Verfasst von), Eric Petitclerc (Verfasst von), René C.-Gaudreault (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2010-06-01T00:00:00Z.
• Schlagworte: article
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PURPOSE. We investigated the involvement of MAPK signaling in the cell death mechanisms of classical microtubule interfering agents (MIA) and aryl-3-(2-chloroethyl)ureas (CEU) acting as antimitotics, along with CEU that don't affect directly microtubules (non-MIA CEU). METHODS. To ascertain the...