Integrated high-throughput analysis identifies super enhancers associated with chemoresistance in SCLC

Abstract Background Chemoresistance is a primary clinical challenge for the management of small cell lung cancer. Additionally, transcriptional regulation by super enhancer (SE) has an important role in tumor evolution. The functions of SEs, a key class of noncoding DNA cis-regulatory elements, have...

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Ngā kaituhi matua: Jiarong Bao (Author), Man Li (Author), Shumei Liang (Author), Yunchu Yang (Author), Jingfang Wu (Author), Qingqing Zou (Author), Shun Fang (Author), Size Chen (Author), Linlang Guo (Author)
Hōputu: Pukapuka
I whakaputaina: BMC, 2019-05-01T00:00:00Z.
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