Bruceine a exerts antitumor effect against colon cancer by accumulating ROS and suppressing PI3K/Akt pathway

• Główni autorzy: Chaozheng Zhang (Autor), Yuening Cao (Autor), Yi Zuo (Autor), Hongbin Cheng (Autor), Changqun Liu (Autor), Xila Xia (Autor), Bo Ren (Autor), Yun Deng (Autor), Maolin Wang (Autor), Jun Lu (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Bruceine A (BA), a quassic ester from bruceine javanica, regulates diverse intracellular signal transduction pathways and manifests a variety of biological activities, however, its pharmacological mechanism in treating colon cancer (CC) is unclear. In this study, we investigated the anticancer effec...