Quantification of cytosine modifications in the aged mouse brain

• Main Authors: Hiroko Sugawara (Author), Akitoshi Date (Author), Satoshi Fuke (Author), Yutaka Nakachi (Author), Tadafumi Kato (Author), Minoru Narita (Author), Miki Bundo (Author), Kazuya Iwamoto (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Quantifying cytosine modifications in various brain regions provides important insights into the gene expression regulation and pathophysiology of neuropsychiatric disorders. In this study, we quantified 5‐methylcytosine (5‐mC), 5‐hydroxymethylation (5‐hmC), and 5‐formylcytosine (5‐fC) leve...