Potency evaluation of unfractionated heparins commercialized in Brazil through anti-factor Xa and anti-factor IIa chromogenic tests and coagulation assay

• Main Authors: Renata Jurema Medeiros (Author), Nathália Pessoa Gonçalves (Author), Magno Maciel Magalhães (Author), João Ferreira Martins (Author), Tiago Savignon Cardoso Machado (Author)
• Format: Book
• Published: Fundação Oswaldo Cruz (FIOCRUZ), 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Heparin is a drug that has anticoagulant activity, binding to antithrombin and accelerating the rate of inhibition of several proteases involved in the coagulation process. In the 2000s, the world market faced a troubled period regarding heparins after reports of allergic reactions and...