Regulatory T cells: the ultimate HIV reservoir?

• Κύριοι συγγραφείς: Joseph Rocco (Συγγραφέας), John W. Mellors (Συγγραφέας), Bernard J.C. Macatangay (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2018-10-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Despite significant advances in the understanding of HIV-1 infection, a cure remains out of reach. This is, in part, due to a long-lived HIV-1 reservoir in resting CD4+ T cells, which do not express viral antigens, and thus are invisible to the immune system. These latently infected cells carry repl...