In Silico Searching for Alternative Lead Compounds to Treat Type 2 Diabetes through a QSAR and Molecular Dynamics Study

• Những tác giả chính: Nicolás Cabrera (Tác giả), Sebastián A. Cuesta (Tác giả), José R. Mora (Tác giả), Luis Calle (Tác giả), Edgar A. Márquez (Tác giả), Roland Kaunas (Tác giả), José Luis Paz (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2022-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Free fatty acid receptor 1 (FFA1) stimulates insulin secretion in pancreatic β-cells. An advantage of therapies that target FFA1 is their reduced risk of hypoglycemia relative to common type 2 diabetes treatments. In this work, quantitative structure-activity relationship (QSAR) approach was used to...