Miglitol, an Anti-diabetic Drug, Inhibits Oxidative Stress-Induced Apoptosis and Mitochondrial ROS Over-Production in Endothelial Cells by Enhancement of AMP-Activated Protein Kinase

• Príomhchruthaitheoirí: Chie Aoki (Údar), Kunihiro Suzuki (Údar), Kazunori Yanagi (Údar), Hiroko Satoh (Údar), Mai Niitani (Údar), Yoshimasa Aso (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2012-01-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Endothelial dysfunction caused by oxidative stress plays a key role in atherogenesis. This study investigated whether the anti-diabetic drug miglitol, an α-glucosidase inhibitor, which is currently available in clinical practice, can prevent endothelial cell apoptosis and whether it might restore im...