Age-related effects of dexmedetomidine on myocardial contraction and coronary circulation in isolated guinea pig hearts

• Main Authors: Maiko Hongo (Author), Susumu Fujisawa (Author), Takeshi Adachi (Author), Tomonori Shimbo (Author), Shigehiro Shibata (Author), Takayoshi Ohba (Author), Kyoichi Ono (Author)
• Format: Book
• Published: Elsevier, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dexmedetomidine is a selective α2 adrenergic agonist. Although dexmedetomidine is widely used for sedation and analgesia, it frequently produces hypotension and bradycardia. The present study aimed to evaluate the effects of dexmedetomidine on cardiac function and coronary circulation using Langendo...