Novel Intrinsic Mechanisms of Active Drug Extrusion at the Blood-Brain Barrier: Potential Targets for Enhancing Drug Delivery to the Brain?
The blood-brain barrier (BBB) limits the pharmacotherapy of several brain disorders. In addition to the structural and metabolic characteristics of the BBB, the ATP-driven, drug efflux transporter P-glycoprotein (Pgp) is a selective gatekeeper of the BBB; thus, it is a primary hindrance to drug deli...
Wedi'i Gadw mewn:
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MDPI AG,
2020-10-01T00:00:00Z.
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Ychwanegu Tag
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Connect to this object online.3rd Floor Main Library
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