Novel Intrinsic Mechanisms of Active Drug Extrusion at the Blood-Brain Barrier: Potential Targets for Enhancing Drug Delivery to the Brain?

The blood-brain barrier (BBB) limits the pharmacotherapy of several brain disorders. In addition to the structural and metabolic characteristics of the BBB, the ATP-driven, drug efflux transporter P-glycoprotein (Pgp) is a selective gatekeeper of the BBB; thus, it is a primary hindrance to drug deli...

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Ngā kaituhi matua: Wolfgang Löscher (Author), Birthe Gericke (Author)
Hōputu: Pukapuka
I whakaputaina: MDPI AG, 2020-10-01T00:00:00Z.
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3rd Floor Main Library

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