Effect of Rifampin‐Mediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel

In vitro studies have indicated that the P2Y12 receptor antagonist selatogrel is a substrate of organic anion‐transporting‐polypeptide (OATP)1B1 and OATP1B3 that are known to mediate hepatic uptake. Selatogrel is primarily eliminated via the biliary route. Therefore, the study aim was to investigate...

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Main Authors: Uta Schilling (Author), Jasper Dingemanse (Author), Christine Voors‐Pette (Author), Christel Romeijn (Author), Peter Dogterom (Author), Mike Ufer (Author)
Format: Book
Published: Wiley, 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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