A Test-Retest Paradigm of the Forced Swimming Test in Female Mice Is Not Valid for Predicting Antidepressant-Like Activity: Participation of Acetylcholine and Sigma-1 Receptors

• मुख्य लेखकों: Jing Su (लेखक), Noriko Hato-Yamada (लेखक), Hiroaki Araki (लेखक), Hiroyuki Yoshimura (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2013-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The forced swimming test (FST) in mice is widely used to predict the antidepressant activity of a drug, but information describing the immobility of female mice is limited. We investigated whether a prior swimming experience affects the immobility duration in a second FST in female mice and whether...