Asymmetric trichotomous partitioning overcomes dataset limitations in building machine learning models for predicting siRNA efficacy

Chemically modified small interfering RNAs (siRNAs) are promising therapeutics guiding sequence-specific silencing of disease genes. Identifying chemically modified siRNA sequences that effectively silence target genes remains challenging. Such determinations necessitate computational algorithms. Ma...

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Main Authors: Kathryn R. Monopoli (Author), Dmitry Korkin (Author), Anastasia Khvorova (Author)
Format: Book
Published: Elsevier, 2023-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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