Genetic and functional role of TNF-alpha in the development Trypanosoma cruzi infection.

• Автори: Cristina Wide Pissetti (Автор), Dalmo Correia (Автор), Rafael Faria de Oliveira (Автор), Maurício Manoel Llaguno (Автор), Marly Aparecida Spadotto Balarin (Автор), Roseane Lopes Silva-Grecco (Автор), Virmondes Rodrigues (Автор)
• Формат: Книга
• Опубліковано: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

TNF-alpha plays an important role in trypanocidal mechanisms and is related to tissue injury. This cytokine has been detected in the heart of human chagasic patients where it is associated with tissue damage. This study investigated whether TNF-alpha levels and the presence of genetic polymorphisms...