IκB kinase promotes Nrf2 ubiquitination and degradation by phosphorylating cylindromatosis, aggravating oxidative stress injury in obesity-related nephropathy
Abstract Background Obesity-related nephropathy (ORN) has become one of the leading causes of end-stage renal disease and has tripled over the past decade. Previous studies have demonstrated that decreased reactive oxygen species production may contribute to improving ORN by ameliorating oxidative s...
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Main Authors: | Yin-Yin Chen (Author), Han Hong (Author), Yu-Ting Lei (Author), Jia Zou (Author), Yi-Ya Yang (Author), Li-Yu He (Author) |
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Format: | Book |
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BMC,
2021-10-01T00:00:00Z.
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