Advances in therapeutic agents targeting quiescent cancer cells

• Main Authors: Wan Najbah Nik Nabil (Author), Zhichao Xi (Author), Mengfan Liu (Author), Yang Li (Author), Mu Yao (Author), Tao Liu (Author), Qihan Dong (Author), Hongxi Xu (Author)
• Format: Book
• Published: Compuscript Ltd, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Quiescent cancer cells (QCCs) reversibly reside in G0 phase, thus allowing them to survive chemotherapy and radiotherapy, which generally target proliferating cells. Surviving QCCs may re-proliferate, and consequently result in cancer progression, recurrence, and metastasis. Therefore, understanding...