Platelet-activating factor acetylhydrolase and haemophagocytosis in the sepsis syndrome

• Main Authors: Franck Trimoreau (Author), Bruno François (Author), Arnaud Desachy (Author), Arnaud Besse (Author), Philippe Vignon (Author), Yves Denizot (Author)
• Format: Book
• Published: Hindawi Limited, 2000-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis syndrome (SS) is associated with depressed PAF acetylhydrolase, the enzyme responsible for the degradation of platelet activating factor. PAF acetylhydrolase is in a large part produced by macrophages, whose inadequate activation with haemophagocytosis is frequent in patients with SS.