Platelet-activating factor acetylhydrolase and haemophagocytosis in the sepsis syndrome

• Autores principales: Franck Trimoreau (Autor), Bruno François (Autor), Arnaud Desachy (Autor), Arnaud Besse (Autor), Philippe Vignon (Autor), Yves Denizot (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2000-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Sepsis syndrome (SS) is associated with depressed PAF acetylhydrolase, the enzyme responsible for the degradation of platelet activating factor. PAF acetylhydrolase is in a large part produced by macrophages, whose inadequate activation with haemophagocytosis is frequent in patients with SS.