Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults

• Main Authors: Schreiner Felix (Author), El-Maarri Osman (Author), Gohlke Bettina (Author), Stutte Sonja (Author), Nuesgen Nicole (Author), Mattheisen Manuel (Author), Fimmers Rolf (Author), Bartmann Peter (Author), Oldenburg Johannes (Author), Woelfle Joachim (Author)
• 格式: 圖書
• 出版: BMC, 2011-09-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Catechol-O-Methyltransferase (COMT) plays a key role in dopamine and estrogen metabolism. Recently, COMT haplotypes rather than the single polymorphism Val158Met have been reported to underlie differences in protein expression by mod...