Suppressive Effects of Transient Receptor Potential Melastatin 8 Agonist on Epileptiform Discharges and Epileptic Seizures

• Main Authors: Hiroshi Moriyama (Author), Sadahiro Nomura (Author), Hirochika Imoto (Author), Takao Inoue (Author), Yuichi Fujiyama (Author), Kohei Haji (Author), Yuichi Maruta (Author), Hideyuki Ishihara (Author), Michiyasu Suzuki (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epilepsy is a relatively common condition, but more than 30% of patients have refractory epilepsy that is inadequately controlled by or is resistant to multiple drug treatments. Thus, new antiepileptic drugs based on newly identified mechanisms are required. A previous report revealed the suppressiv...