Design and Synthesis of New Pyrimidine-Quinolone Hybrids as Novel <i>h</i>LDHA Inhibitors

A battery of novel pyrimidine-quinolone hybrids was designed by docking scaffold replacement as lactate dehydrogenase A (<i>h</i>LDHA) inhibitors. Structures with different linkers between the pyrimidine and quinolone scaffolds (<b>10</b>-<b>21</b> and <b>24...

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Main Authors: Iván Díaz (Author), Sofia Salido (Author), Manuel Nogueras (Author), Justo Cobo (Author)
Format: Book
Published: MDPI AG, 2022-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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