Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy

• Main Authors: Wenwen Wang (Author), Liwei Wu (Author), Jingjing Li (Author), Jie Ji (Author), Kan Chen (Author), Qiang Yu (Author), Sainan Li (Author), Jiao Feng (Author), Tong Liu (Author), Jie Zhang (Author), Jiaojiao Chen (Author), Yuting Zhou (Author), Yuqing Mao (Author), Fan Wang (Author), Weiqi Dai (Author), Xiaoming Fan (Author), Chuanyong Guo (Author), Jianye Wu (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatic ischemia reperfusion (IR) injury (IRI) occurs during liver transplantation, hepatectomy, and hemorrhagic shock. Oleanolic acid (OA) is a natural compound with antioxidant and anti-inflammatory activity that has been used to treat liver disorders in clinical practice for several years. Here,...