Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer

• Main Authors: Elizabeth V. Connor (Author), Caner Saygin (Author), Chad Braley (Author), Andrew C. Wiechert (Author), Sheelarani Karunanithi (Author), Katie Crean-Tate (Author), Fadi W. Abdul-Karim (Author), Chad M. Michener (Author), Peter G. Rose (Author), Justin D. Lathia (Author), Ofer Reizes (Author)
• Formato: Livro
• Publicado em: BMC, 2019-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Ovarian cancer is the leading cause of gynecologic cancer death in the United States despite effective first-line systemic chemotherapy. Cancer stem cells (CSCs) retain the ability to self-renew and proliferate and may be a means of harboring disease that evades standard treatmen...