Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• Κύριοι συγγραφείς: Lisa Nadal (Συγγραφέας), Riccardo Corbellari (Συγγραφέας), Alessandra Villa (Συγγραφέας), Tobias Weiss (Συγγραφέας), Michael Weller (Συγγραφέας), Dario Neri (Συγγραφέας), Roberto De Luca (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...