Orofacial antinociceptive effects of perillyl alcohol associated with codeine and its possible modes of action

• Main Authors: Rebecca Rhuanny Tolentino LIMEIRA (Author), Natália Viana DANTAS (Author), James Felipe TOMAZ-MORAIS (Author), Tereza Karla Vieira Lopes da COSTA (Author), Renan Marinho BRAGA (Author), Frederico Barbosa SOUSA (Author), Luciana SCOTTI (Author), Mirian Graciela da Silva Stiebbe SALVADORI (Author), Reinaldo Nóbrega de ALMEIDA (Author), Ricardo Dias CASTRO (Author)
• Format: Book
• Published: Sociedade Brasileira de Pesquisa Odontológica, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This study evaluated the orofacial antinociceptive effect of (S)-(-)-perillyl alcohol (PA) associated with codeine (C) and investigated the possible molecular anchorage mechanisms of PA. Mice (n = 5 per group) were treated with PA alone and associated with codeine and assigned to the follow...