Interaction Between NOS3 and HMOX1 on Antihypertensive Drug Responsiveness in Preeclampsia

• Main Authors: Valeria Cristina Sandrim (Author), Marcelo Rizzatti Luizon (Author), Eliane Pilan (Author), Mayara Caldeira-Dias (Author), Fernanda Borchers Coeli-Lacchini (Author), Georgia Kors (Author), Iuly Berndt (Author), Riccardo Lacchini (Author), Ricardo Carvalho Cavalli (Author)
• Format: Book
• Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective We examined the interaction of polymorphisms in the genes heme oxygenase- 1 (HMOX1) and nitric oxide synthase (NOS3) in patients with preeclampsia (PE) as well as the responsiveness to methyldopa and to total antihypertensive therapy. Methods The genes HMOX1 (rs2071746, A/T) and N...