Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis

• Main Authors: Micah Silaba, MMed (Author), Michael Ooko, MSc (Author), Christian Bottomley, PhD (Author), Joyce Sande, MMed (Author), Rachel Benamore, FRCR (Author), Kate Park, FRCR (Author), James Ignas, MD (Author), Kathryn Maitland, FMedSci (Author), Neema Mturi, MMed (Author), Anne Makumi, MSc (Author), Mark Otiende, MSc (Author), Stanley Kagwanja, Dip MIS (Author), Sylvester Safari, Dip MIS (Author), Victor Ochola, BSc (Author), Tahreni Bwanaali, MBA (Author), Evasius Bauni, PhD (Author), Fergus Gleeson, FRCR (Author), Maria Deloria Knoll, PhD (Author), Ifedayo Adetifa, PhD (Author), Kevin Marsh, FMedSci (Author), Thomas N Williams, FMedSci (Author), Tatu Kamau, MPH (Author), Shahnaaz Sharif, MD (Author), Orin S Levine, PhD (Author), Laura L Hammitt, MD (Author), J Anthony G Scott, FMedSci (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Pneumococcal conjugate vaccines (PCV) are highly protective against invasive pneumococcal disease caused by vaccine serotypes, but the burden of pneumococcal disease in low-income and middle-income countries is dominated by pneumonia, most of which is non-bacteraemic. We examine...