Repurposing of Sitagliptin- Melittin Optimized Nanoformula against SARS-CoV-2; Antiviral Screening and Molecular Docking Studies

• Main Authors: Mohammed W. Al-Rabia (Author), Nabil A. Alhakamy (Author), Osama A. A. Ahmed (Author), Khalid Eljaaly (Author), Ahmed L. Alaofi (Author), Ahmed Mostafa (Author), Hani Z. Asfour (Author), Ahmed A. Aldarmahi (Author), Khaled M. Darwish (Author), Tarek S. Ibrahim (Author), Usama A. Fahmy (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The outbreak of the COVID-19 pandemic in China has become an urgent health and economic challenge. The objective of the current work was to evaluate the efficacy of the combined complex of Sitagliptin (SIT) with melittin (MEL) against SARS-CoV-2 virus. SIT-MEL nano-conjugates were optimized by a ful...