Targeting Streptococcus pneumoniae UDP-glucose pyrophosphorylase (UGPase): in vitro validation of a putative inhibitor

Background: Genome plasticity of Streptococcus pneumoniae is responsible for the reduced efficacy of various antibiotics and capsular polysaccharide based vaccines. Therefore targets independent of capsular types are sought to control the pneumococcal pathogenicity. UcrDP-glucose pyrophosphorylase (...

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Main Authors: Monica Sharma (Author), Swati Sharma (Author), Pallab Ray (Author), Anuradha Chakraborti (Author)
Format: Book
Published: AboutScience Srl, 2020-10-01T00:00:00Z.
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