ECM1 regulates the resistance of colorectal cancer to 5-FU treatment by modulating apoptotic cell death and epithelial-mesenchymal transition induction

5-Fluorouracil (5-FU) chemoresistance is a persistent impediment to the efficient treatment of many types of cancer, yet the molecular mechanisms underlying such resistance remain incompletely understood. Here we found CRC patients resistant to 5-FU treatment exhibited increased extracellular matrix...

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Prif Awduron: Sirui Long (Awdur), Jie Wang (Awdur), Fanbin Weng (Awdur), Zhigang Pei (Awdur), Shixian Zhou (Awdur), Guiyin Sun (Awdur), Debing Xiang (Awdur)
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Cyhoeddwyd: Frontiers Media S.A., 2022-11-01T00:00:00Z.
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