Xanthohumol Inhibited Mechanical Stimulation-Induced Articular ECM Degradation by Mediating lncRNA GAS5/miR-27a Axis

• Main Authors: Tiansheng Zheng (Author), Qingluo Zhou (Author), Jishang Huang (Author), Jinliang Lai (Author), Guanglin Ji (Author), Dechao Kong (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Osteoarthritis (OA) is histopathologically marked by extracellular matrix (ECM) degradation in joint cartilage. Abnormal mechanical stimulation on joint cartilage may result in ECM degeneration and OA development. Matrix metalloproteinase 13 (MMP-13) is one of the catabolic enzymes contributing to t...