A Simplified Herbal Formula Improves Cardiac Function and Reduces Inflammation in Mice Through the TLR-Mediated NF-κB Signaling Pathway

• Main Authors: Xiaoming Dong (Author), Xiaowei Han (Author), Xiaojiao Zhang (Author), Sijing Li (Author), Ziru Li (Author), Jinhua Kang (Author), Jialin Jiang (Author), Shihao Ni (Author), Lu Lu (Author), Zhiling He (Author), Haoming Huang (Author), Shaoxiang Xian (Author), Tianhui Yuan (Author), Zhongqi Yang (Author), Wenjie Long (Author), Zemin Wan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nuanxinkang tablet (NXK), a Chinese herbal formula, can improve heart function and quality of life in patients with chronic heart failure (CHF). However, the mechanisms of action of NXK are not fully understood. In this study, we investigated the effects of NXK on inflammation in the CHF mouse model...