Preclinical Therapeutic Assessment of a New Chemotherapeutics [Dichloro(4,4'-Bis(2,2,3,3-Tetrafluoropropoxy) Methyl)-2,2'-Bipryridine) Platinum] in an Orthotopic Patient-Derived Xenograft Model of Triple-Negative Breast Cancers

Cisplatin is one of the most common therapeutics used in treatments of several types of cancers. To enhance cisplatin lipophilicity and reduce resistance and side effects, a polyfluorinated bipyridine-modified cisplatin analogue, dichloro[4,4'-bis(2,2,3,3-tetrafluoropropoxy)methyl)-2,2'-bi...

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Main Authors: Tzu-Chun Kan (Author), Mei-Hsiang Lin (Author), Chun-Chia Cheng (Author), Jeng-Wei Lu (Author), Ming-Thau Sheu (Author), Yuan-Soon Ho (Author), Sri Rahayu (Author), Jungshan Chang (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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