Immunomodulation and Antioxidant Activities as Possible Trypanocidal and Cardioprotective Mechanisms of Major Terpenes from <i>Lippia alba</i> Essential Oils in an Experimental Model of Chronic Chagas Disease

• Egile Nagusiak: Denerieth Ximena Espinel-Mesa (Egilea), Clara Isabel González Rugeles (Egilea), Julio César Mantilla Hernández (Egilea), Elena E. Stashenko (Egilea), Carlos Andrés Villegas-Lanau (Egilea), John Jaime Quimbaya Ramírez (Egilea), Liliana Torcoroma García Sánchez (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

In the late phase of <i>Trypanosoma cruzi</i> infection, parasite persistence and an exaggerated immune response accompanied by oxidative stress play a crucial role in the genesis of Chronic Chagasic Cardiomyopathy (CCC). Current treatments (Benznidazole (BNZ) and Nifurtimox) can effect...