Immunomodulation and Antioxidant Activities as Possible Trypanocidal and Cardioprotective Mechanisms of Major Terpenes from <i>Lippia alba</i> Essential Oils in an Experimental Model of Chronic Chagas Disease

• Main Authors: Denerieth Ximena Espinel-Mesa (Author), Clara Isabel González Rugeles (Author), Julio César Mantilla Hernández (Author), Elena E. Stashenko (Author), Carlos Andrés Villegas-Lanau (Author), John Jaime Quimbaya Ramírez (Author), Liliana Torcoroma García Sánchez (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the late phase of <i>Trypanosoma cruzi</i> infection, parasite persistence and an exaggerated immune response accompanied by oxidative stress play a crucial role in the genesis of Chronic Chagasic Cardiomyopathy (CCC). Current treatments (Benznidazole (BNZ) and Nifurtimox) can effect...