EZH2 is involved in psoriasis progression by impairing miR-125a-5p inhibition of SFMBT1 and leading to inhibition of the TGFβ/SMAD pathway

Aims: In this study, we aimed to decipher the impact of enhancer of zeste homolog 2 (EZH2) in psoriasis as well as the underlying mechanism. Methods: A mouse model of psoriasis was developed by means of imiquimod induction, with the expression of EZH2, microRNA-125a-5p (miR-125a-5p), and SFMBT1 dete...

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Main Authors: Shengming Qu (Author), Zhe Liu (Author), Bing Wang (Author)
Format: Book
Published: SAGE Publishing, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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