Deprivation of L-Arginine Induces Oxidative Stress Mediated Apoptosis in Leishmania donovani Promastigotes: Contribution of the Polyamine Pathway.

• Main Authors: Abhishek Mandal (Author), Sushmita Das (Author), Saptarshi Roy (Author), Ayan Kumar Ghosh (Author), Abul Hasan Sardar (Author), Sudha Verma (Author), Savita Saini (Author), Ruby Singh (Author), Kumar Abhishek (Author), Ajay Kumar (Author), Chitra Mandal (Author), Pradeep Das (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The growth and survival of intracellular parasites depends on the availability of extracellular nutrients. Deprivation of nutrients viz glucose or amino acid alters redox balance in mammalian cells as well as some lower organisms. To further understand the relationship, the mechanistic role of L-arg...