Discovery of Quercetin and Its Analogs as Potent OXA-48 Beta-Lactamase Inhibitors

• Main Authors: Yuejuan Zhang (Author), Cheng Chen (Author), Bin Cheng (Author), Lei Gao (Author), Chuan Qin (Author), Lixia Zhang (Author), Xu Zhang (Author), Jun Wang (Author), Yi Wan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Carbapenem resistance in Enterobacteriaceae caused by OXA-48 β-lactamase is a growing global health threat and has rapidly spread in many regions of the world. Developing inhibitors is a promising way to overcome antibiotic resistance. However, there are few options for problematic OXA-48. Here we i...