Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury

• Hauptverfasser: Meng Zhao (Verfasst von), Yijie Zhou (Verfasst von), Shuyun Liu (Verfasst von), Lan Li (Verfasst von), Younan Chen (Verfasst von), Jingqiu Cheng (Verfasst von), Yanrong Lu (Verfasst von), Jingping Liu (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Persistent mitochondrial injury occurs after acute kidney injury (AKI) and mitochondria-targeted antioxidant Mito-2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) (MT) has shown benefits for AKI, but its efficiency is limited by short half-life and side effect in vivo. Self-assembling peptide (SAP) hydr...