Synthesis of crocetin derivatives and their potent inhibition in multiple tumor cells proliferation and inflammatory property of macrophage

• Main Authors: Mao-Ze Wang (Author), Jin Gao (Author), Yang Chu (Author), Jie Niu (Author), Ming Chen (Author), Qiang Shang (Author), Li-Hua Peng (Author), Zhi-Hong Jiang (Author)
• Format: Book
• Published: BMC, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Crocetin is a major active component of saffron, which has a wide range of pharmacological effects. However, due to its low solubility, the pharmacological effects of crocetin cannot be better utilized. Methods In this study, we modified the chemical structure of crocetin by conj...