Disease-associated pathophysiologic structures in pediatric rheumatic diseases show characteristics of scale-free networks seen in physiologic systems: implications for pathogenesis and treatment

• Main Authors: McGhee Timothy (Author), Chaser Brad (Author), McKee Ryan (Author), Chen Yanmin (Author), Jiang Kaiyu (Author), Knowlton Nicholas (Author), Aggarwal Amita (Author), Wang Shirley (Author), Frank Mark (Author), Osban Jeanette (Author), Jarvis James N (Author)
• Format: Book
• Published: BMC, 2009-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>While standard reductionist approaches have provided some insights into specific gene polymorphisms and molecular pathways involved in disease pathogenesis, our understanding of complex traits such as atherosclerosis or type 2 diabet...