Yang-Yin-Jie-Du decoction overcomes gefitinib resistance in non-small cell lung cancer via down-regulation of the PI3K/Akt signalling pathway

• المؤلفون الرئيسيون: Shu-yi Chen (مؤلف), Gao- (مؤلف), Qi-jin Shu (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Context Yang-Yin-Jie-Du Decoction (YYJDD) was used to improve gefitinib efficacy in our clinical practice, but its mechanism remains unclear. Objective This study explored if YYJDD could reverse gefitinib resistance. Materials and methods H1975 cells were exposed to control, 10 μM gefitinib, 3.2 mg/...