Neutrophil extracellular traps and heparin-induced antibodies contribute to vascular access thrombosis in hemodialysis patients

• Main Authors: Hoi Woul Lee (Author), Jung Nam An (Author), Hyung Seok Lee (Author), Young Rim Song (Author), Hyung Jik Kim (Author), Sung Gyun Kim (Author), Jwa-Kyung Kim (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Anti-heparin/platelet factor 4 (PF4) antibodies may trigger severe thrombotic complications in hemodialysis (HD) patients. Tetrameric PF4 has a high affinity for extracellular DNA, which is a key component of neutrophil extracellular traps (NETs); therefore, the interactions between anti-...