Association study of a single nucleotide polymorphism in the hypoxia response element of the macrophage migration inhibitory factor gene promoter with suicide completers in the Japanese population

• Main Authors: Toshiyuki Shirai (Author), Satoshi Okazaki (Author), Takaki Tanifuji (Author), Ikuo Otsuka (Author), Masao Miyachi (Author), Shohei Okada (Author), Ryota Shindo (Author), Tadasu Horai (Author), Kentaro Mouri (Author), Motonori Takahashi (Author), Takeshi Kondo (Author), Yasuhiro Ueno (Author), Akitoyo Hishimoto (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background More than 800 000 people die by suicide annually. The heritability of suicide is 30%-50%. We focused on the hypoxia response element (HRE), which promotes the expression of macrophage migration inhibitory factor (MIF) via the hypoxia‐inducible factor (HIF) pathway, important in n...