A perspective on oligonucleotide therapy: Approaches to patient customization

• Главные авторы: Shikha Thakur (Автор), Apurba Sinhari (Автор), Priti Jain (Автор), Hemant R. Jadhav (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

It is estimated that the human genome encodes 15% of proteins that are considered to be disease-modifying. Only 2% of these proteins possess a druggable site that the approved clinical candidates target. Due to this disparity, there is an immense need to develop therapeutics that may better mitigate...