Effect of ABCB1 Gene Carriage and Drug-Drug Interactions on Apixaban and Rivaroxaban Pharmacokinetics and Clinical Outcomes in Patients with Atrial Fibrillation and Deep Vein Thrombosis

• Main Authors: L. V. Fedina (Author), I. N. Sychev (Author), T. D. Rastvorova (Author), E. V. Strigunkova (Author), A. A. Kachanova (Author), Z. A. Sozaeva (Author), P. O. Bochkov (Author), A. V. Vardanyan (Author), K. B. Mirzayev (Author), D. A. Sychev (Author)
• Format: Book
• Published: Столичная издательская компания, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim. To investigate the effect of ABCB1 gene carriage and interdrug interactions on apixaban pharmacokinetics and clinical outcomes in patients with atrial fibrillation and deep vein thrombosis.Material and methods. Patients hospitalized at Yudin State Clinical Hospital participated in the study. A...